—________. — Ever since last week. A. Have you taken your temperature? B. What’s the matter with yo

—________. — Ever since last week. A. Have you taken your temperature? B. What’s the matter with you? C. Is there anything wrong with you? D. How long have you been like this？

The most natural choice for the conversation would be:

D. How long have you been like this?

This option fits well because it asks about the duration of the situation implied by "ever since last week."