CD8

1.Previous work demonstrates that islet allografts do not primarily initiate rejection by the (CD4-independent) CD8-dependent pathway.先前的研究提示胰岛细胞移植物并不会通过（非CD4依赖性）CD8依赖性途径原发性产生排斥反应。

2.However, CD8 T(EM) were significantly better than T(CM) at rejecting allografts in the absence of secondary lymphoid tissues.但是，CD8T（EM）这在缺少次级淋巴组织宿主排斥反应的移植物中明显优于T（CM）。

3.However, CD8 T were significantly better than T at rejecting allografts in the absence of secondary lymphoid tissues.但是，在发生排斥反应的无次级淋巴样组织的移植物中，CD8T明显优于T。

4.Hepatology Digest: You mentioned that there distinct differences of CD8 T cells in HCV patients . Can you please elaborate on this?《国际肝病》：您曾提到，丙型肝炎患者之间的CD8+T细胞存在明显区别。您能详细解释一下吗？

5.Conclusions The acute rejection of renal allograft is mainly a T lymphocyte, especially CD8 lymphocyte mediated immunopathologic process.结论移植肾急性排斥反应主要是由T淋巴细胞尤其是CD8细胞介导的一种免疫损伤。

6.CD8+ T cells are the main effector cells for the immune control of cytomegaloviruses.CD8+T细胞是主要的效应细胞的免疫控制的巨细胞病毒。

7.Thus, Histoplasma-induced host cell apoptosis would be key to CD8 T cell activation in the infected host.因此，组织胞浆菌所引起之宿主细胞的死亡对于感染后宿主体内CD8T细胞的活化是很重要的。

8.Donor - reactive CD8 memory T - cell infiltration, proliferation and ICOS expression are regulated by donor class I MHC molecule expression.供者MHC-I类分子的表达能够调节供者反应性CD8记忆T细胞浸润、增殖以及ICOS的表达。

9.Instead at the CTL transition stage, B cell deficiency resulted in apoptosis of intra-islet CTL.细胞缺陷引起胰岛内CTL细胞凋亡但不影响CD8+T淋巴细胞向CTL转化。

10.In conclusion, HCV-specific CD8+ cells inhibit viral RNA replication by cytokine-mediated and direct cytolytic effects.总之，HCV特异性CD8+细胞通过细胞因子介导和直接溶细胞效应抑制了病毒RNA的复制。